General Information
SPKB ID SPKB02525
Signal sequence MAPPGSSTVFLLALTIIASTWA
Length 22
Organism Homo sapiens (Human)
UniProt ID P04844,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6S7O,
Predicted Structure ID SPKB02525.cif
Physicochemical Information
Molecular weight 2247.67764
Aliphatic index 120
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 794.01
Aromaticity 0.090909091
Average rotatable bonds 2.954545455
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 30
X logP energy -5.9719
Hydropathy 
Literature Information
Title Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
DOI 10.1038/nbt810,
Publication Year 2003
PubMed ID 12665801,
Patent ID NA,
