General Information
SPKB ID SPKB02524
Signal sequence MLSRALLCLALAWAARVGA
Length 19
Organism Rattus norvegicus (Rat)
UniProt ID P04785,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02524.cif
Physicochemical Information
Molecular weight 1986.46734
Aliphatic index 149.4736842
Isoelectric point 10.52640717
Charge (pH=7) 1.936002961
Topological polar surface area 746.94
Aromaticity 0.052631579
Average rotatable bonds 3.315789474
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 25
X logP energy -4.31226
Hydropathy
Literature Information
Title Identification of protein disulfide isomerase and calreticulin as autoimmune antigens in LEC strain of rats.
DOI 10.1016/0304-4165(93)90033-5,
Publication Year 1993
PubMed ID 8251535,
Patent ID NA,