SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02524

Signal sequence   MLSRALLCLALAWAARVGA

Length  19

Organism  Rattus norvegicus (Rat)

UniProt ID  P04785,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02524.cif

Structure  SPKB02524.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1986.46734

Aliphatic index  149.4736842

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  746.94

Aromaticity  0.052631579

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  25

X logP energy  -4.31226

Hydropathy 



Literature Information


Title  Identification of protein disulfide isomerase and calreticulin as autoimmune antigens in LEC strain of rats.

DOI  10.1016/0304-4165(93)90033-5,

Publication Year  1993

PubMed ID  8251535,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.