SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02523

Signal sequence   MKLLILTCLVAVALA

Length  15

Organism  Ovis aries (Sheep)

UniProt ID  P04653,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02523.cif

Structure  SPKB02523.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1572.08384

Aliphatic index  214.6666667

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  516.97

Aromaticity  0

Average rotatable bonds  3.466666667

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  20

X logP energy  0.0265

Hydropathy 



Literature Information


Title  Primary structure of ovine alpha s1-caseins: localization of phosphorylation sites and characterization of genetic variants A, C and D.

DOI  10.1017/s0022029900030983,

Publication Year  1995

PubMed ID  7601973,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.