SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02522

Signal sequence   MKAAVLAVALVFLTGCQA

Length  18

Organism  Rattus norvegicus (Rat)

UniProt ID  P04639,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02522.cif

Structure  SPKB02522.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1806.25504

Aliphatic index  141.1111111

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  647.36

Aromaticity  0.055555556

Average rotatable bonds  3.222222222

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  24

X logP energy  -3.822

Hydropathy 



Literature Information


Title  The primary translation product of rat intestinal apolipoprotein A-I mRNA is an unusual preproprotein.

DOI  NA,

Publication Year  1982

PubMed ID  6798036,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.