General Information
SPKB ID SPKB02519
Signal sequence MAVMAPRTLLLLLSGALALTQTWA
Length 24
Organism Homo sapiens (Human)
UniProt ID P04439,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8RBU,
Predicted Structure ID SPKB02519.cif
Physicochemical Information
Molecular weight 2542.13634
Aliphatic index 146.6666667
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 925.53
Aromaticity 0.041666667
Average rotatable bonds 3.333333333
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 33
X logP energy -5.34183
Hydropathy
Literature Information
Title Comparison of amino acid sequences of two human histocompatibility antigens, HLA-A2 and HLA-B7: location of putative alloantigenic sites.
Publication Year 1979
PubMed ID 92029,
Patent ID NA,