SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02515

Signal sequence   MESRGPLATSRLLLLLLLLLLRHTRQGWA

Length  29

Organism  Homo sapiens (Human)

UniProt ID  P04278,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02515.cif

Structure  SPKB02515.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3329.05644

Aliphatic index  154.8275862

Isoelectric point  12.50005509

Charge (pH=7)   3.090655268

Topological polar surface area  1322.71

Aromaticity  0.034482759

Average rotatable bonds  3.827586207

Number of hydrogen bond donors  49

Number of hydrogen bond acceptors  42

X logP energy  -8.33892

Hydropathy 



Literature Information


Title  Amino acid sequence of the sex steroid binding protein of human blood plasma.

DOI  10.1021/bi00371a048,

Publication Year  1986

PubMed ID  3542030,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.