SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02514

Signal sequence   MKRVLVLLLALAFGHA

Length  16

Organism  Rattus norvegicus (Rat)

UniProt ID  P04276,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02514.cif

Structure  SPKB02514.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1752.23764

Aliphatic index  176.875

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  616.42

Aromaticity  0.0625

Average rotatable bonds  3.625

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  21

X logP energy  -0.74223

Hydropathy 



Literature Information


Title  The amino acid sequence of the NH2-terminal portion of rat and human vitamin D binding protein: evidence for a high degree of homology between rat and human vitamin D binding protein.

DOI  10.1016/0024-3205(86)90569-2,

Publication Year  1986

PubMed ID  3713442,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.