General Information
SPKB ID SPKB02513
Signal sequence MIPARFAGVLLALALILPGTLC
Length 22
Organism Homo sapiens (Human)
UniProt ID P04275,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7KWO,
Predicted Structure ID SPKB02513.cif
Physicochemical Information
Molecular weight 2253.87604
Aliphatic index 173.1818182
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 738.97
Aromaticity 0.045454545
Average rotatable bonds 3.136363636
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 27
X logP energy -1.47163
Hydropathy 
Literature Information
Title Evolution of human von Willebrand factor: cDNA sequence polymorphisms, repeated domains, and relationship to von Willebrand antigen II.
DOI 10.1016/s0006-291x(87)80016-5,
Publication Year 1987
PubMed ID 3495266,
Patent ID NA,
