SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02512

Signal sequence   MSMLVVFLLLWGVTWGPVTEA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P04217,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02512.cif

Structure  SPKB02512.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2349.87464

Aliphatic index  134.2857143

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  766.1

Aromaticity  0.142857143

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -0.4928

Hydropathy 



Literature Information


Title  Amino acid sequence of human plasma alpha 1B-glycoprotein: homology to the immunoglobulin supergene family.

DOI  10.1073/pnas.83.8.2363,

Publication Year  1986

PubMed ID  3458201,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.