SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02511

Signal sequence   MKALIAALLLITLQYSCA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P04196,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02511.cif

Structure  SPKB02511.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1936.44174

Aliphatic index  173.8888889

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  687.82

Aromaticity  0.055555556

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -2.559

Hydropathy 



Literature Information


Title  Plasma protein map: an update by microsequencing.

DOI  10.1002/elps.11501301150,

Publication Year  1992

PubMed ID  1459097,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.