SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02509

Signal sequence   MRSKKLWISLLFALTLIFTMAFSNMSAQA

Length  29

Organism  Bacillus subtilis (strain 168)

UniProt ID  P04189,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02509.cif

Structure  SPKB02509.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3321.06024

Aliphatic index  107.9310345

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1215.41

Aromaticity  0.137931034

Average rotatable bonds  3.827586207

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  44

X logP energy  -7.52063

Hydropathy 



Literature Information


Title  Determination of the signal peptidase cleavage site in the preprosubtilisin of Bacillus subtilis.

DOI  NA,

Publication Year  1986

PubMed ID  3090033,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.