SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02506

Signal sequence   MPRLFFFHLLGVCLLLNQFSRAVA

Length  24

Organism  Homo sapiens (Human)

UniProt ID  P04090,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02506.cif

Structure  SPKB02506.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2793.42964

Aliphatic index  130

Isoelectric point  10.5273869

Charge (pH=7)   2.026912052

Topological polar surface area  982.72

Aromaticity  0.166666667

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  33

X logP energy  -3.40606

Hydropathy 



Literature Information


Title  Human seminal relaxin is a product of the same gene as human luteal relaxin.

DOI  10.1210/endo.130.5.1572287,

Publication Year  1992

PubMed ID  1572287,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.