SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02505

Signal sequence   MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASG

Length  39

Organism  Homo sapiens (Human)

UniProt ID  P04062,

Motif  1..39



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6T13,

Predicted Structure ID  SPKB02505.cif

Structure  SPKB02505.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4136.80924

Aliphatic index  92.56410256

Isoelectric point  6.433483633

Charge (pH=7)   -0.058966705

Topological polar surface area  1645.42

Aromaticity  0.051282051

Average rotatable bonds  3.435897436

Number of hydrogen bond donors  59

Number of hydrogen bond acceptors  59

X logP energy  -17.83476

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.