SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02503

Signal sequence   MKLLVLAVLLTVAAA

Length  15

Organism  Homo sapiens (Human)

UniProt ID  P04054,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02503.cif

Structure  SPKB02503.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1525.99704

Aliphatic index  214.6666667

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  516.97

Aromaticity  0

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  18

Number of hydrogen bond acceptors  19

X logP energy  -0.2735

Hydropathy 



Literature Information


Title  Studies on prophospholipase A2 and its enzyme from human pancreatic juice. Catalytic properties and sequence of the N-terminal region.

DOI  10.1111/j.1432-1033.1982.tb05855.x,

Publication Year  1982

PubMed ID  7060561,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.