General Information
SPKB ID SPKB02502
Signal sequence MAPLRPLLILALLAWVALA
Length 19
Organism Homo sapiens (Human)
UniProt ID P04004,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02502.cif
Physicochemical Information
Molecular weight 2045.64374
Aliphatic index 205.7894737
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 647.23
Aromaticity 0.052631579
Average rotatable bonds 3.210526316
Number of hydrogen bond donors 22
Number of hydrogen bond acceptors 22
X logP energy 2.00177
Hydropathy 
Literature Information
Title Primary structure of somatomedin B: a growth hormone-dependent serum factor with protease inhibiting activity.
DOI 10.1016/0014-5793(78)80132-x,
Publication Year 1978
PubMed ID 631332,
Patent ID NA,
