General Information
SPKB ID SPKB02501
Signal sequence MHPPKTPSGALHRKRKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLG
Length 48
Organism Homo sapiens (Human)
UniProt ID P04003,
Motif 1..48
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02501.cif
Physicochemical Information
Molecular weight 5380.55444
Aliphatic index 97.70833333
Isoelectric point 12.28022265
Charge (pH=7) 6.179058896
Topological polar surface area 1938.54
Aromaticity 0.083333333
Average rotatable bonds 3.5
Number of hydrogen bond donors 67
Number of hydrogen bond acceptors 68
X logP energy -10.76099
Hydropathy
Literature Information
Title Amino acid sequence studies of human C4b-binding protein: N-terminal sequence analysis and alignment of the fragments produced by limited proteolysis with chymotrypsin and the peptides produced by cyanogen bromide treatment.
DOI 10.1016/0161-5890(85)90127-0,
Publication Year 1985
PubMed ID 4033666,
Patent ID NA,