SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02500

Signal sequence   MALSLFTVGQLIFLFWTMRITEA

Length  23

Organism  Pseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus)

UniProt ID  P04002,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02500.cif

Structure  SPKB02500.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2689.26914

Aliphatic index  123.0434783

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  942.52

Aromaticity  0.173913043

Average rotatable bonds  3.739130435

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -2.84573

Hydropathy 



Literature Information


Title  Biosynthesis of antifreeze polypeptides in the winter flounder. Characterization and seasonal occurrence of precursor polypeptides.

DOI  10.1111/j.1432-1033.1986.tb09966.x,

Publication Year  1986

PubMed ID  3769927,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.