SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02498

Signal sequence   MRDLPLTSLALVLSALGALLGTEA

Length  24

Organism  Homo sapiens (Human)

UniProt ID  P03971,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02498.cif

Structure  SPKB02498.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2425.90954

Aliphatic index  158.75

Isoelectric point  4.184407676

Charge (pH=7)   -0.999797405

Topological polar surface area  941.25

Aromaticity  0

Average rotatable bonds  3.291666667

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -7.47583

Hydropathy 



Literature Information


Title  Proteolytic processing of mullerian inhibiting substance produces a transforming growth factor-beta-like fragment.

DOI  NA,

Publication Year  1988

PubMed ID  2974034,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.