SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02496

Signal sequence   MVMGLGVLLLVFVLGLGLTPPTLA

Length  24

Organism  Homo sapiens (Human)

UniProt ID  P03950,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9BDL,

Predicted Structure ID  SPKB02496.cif

Structure  SPKB02496.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2425.11264

Aliphatic index  182.5

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  755.5

Aromaticity  0.041666667

Average rotatable bonds  3.125

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  29

X logP energy  -0.3901

Hydropathy 



Literature Information


Title  Amino acid sequence of human tumor derived angiogenin.

DOI  10.1021/bi00341a031,

Publication Year  1985

PubMed ID  2866794,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.