SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02494

Signal sequence   MYGIEYTTVLTFLISIILLNYILKSLTRIMDCIIYRLLFIIVILSPFLRA

Length  50

Organism  Rotavirus A (strain RVA/SA11-Both/G3P5B[2]) (RV-A) (Simian Agent 11 (strain Both))

UniProt ID  P03533,

Motif  1..50



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02494.cif

Structure  SPKB02494.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5898.33254

Aliphatic index  177.4

Isoelectric point  9.135232377

Charge (pH=7)   1.934524566

Topological polar surface area  2032.37

Aromaticity  0.14

Average rotatable bonds  3.86

Number of hydrogen bond donors  75

Number of hydrogen bond acceptors  72

X logP energy  -2.81779

Hydropathy 



Literature Information


Title  Processing of rotavirus glycoprotein VP7: implications for the retention of the protein in the endoplasmic reticulum.

DOI  10.1083/jcb.105.6.2897,

Publication Year  1987

PubMed ID  2826493,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.