General Information
SPKB ID SPKB02490
Signal sequence MKKLLPILIGLSLSGFSSLSQA
Length 22
Organism Escherichia coli (strain K12)
UniProt ID P02930,
Motif 1..22
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Cell membrane
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 5NG5,
Predicted Structure ID SPKB02490.cif
Physicochemical Information
Molecular weight 2303.82884
Aliphatic index 146.3636364
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 861.91
Aromaticity 0.045454545
Average rotatable bonds 3.590909091
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 32
X logP energy -6.7824
Hydropathy
Literature Information
Title Identification and characterization of the TolC protein, an outer membrane protein from Escherichia coli.
DOI 10.1128/jb.153.2.693-699.1983,
Publication Year 1983
PubMed ID 6337123,
Patent ID NA,