SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02489

Signal sequence   MNMKKLATLVSAVALSATVSANAMA

Length  25

Organism  Escherichia coli (strain K12)

UniProt ID  P02925,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02489.cif

Structure  SPKB02489.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2494.02124

Aliphatic index  109.6

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  1001.09

Aromaticity  0

Average rotatable bonds  3.36

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  38

X logP energy  -11.7143

Hydropathy 



Literature Information


Title  FIS is a regulator of metabolism in Escherichia coli.

DOI  10.1111/j.1365-2958.1996.tb02652.x,

Publication Year  1996

PubMed ID  8899705,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.