SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02485

Signal sequence   MGTWILFACLLGAAFS

Length  16

Organism  Bos taurus (Bovine)

UniProt ID  P02817,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02485.cif

Structure  SPKB02485.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1701.07414

Aliphatic index  116.25

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  556.07

Aromaticity  0.1875

Average rotatable bonds  3.1875

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  21

X logP energy  -1.5574

Hydropathy 



Literature Information


Title  Amelogenin post-translational modifications: carboxy-terminal processing and the phosphorylation of bovine and porcine "TRAP" and "LRAP" amelogenins.

DOI  10.1006/bbrc.1993.2468,

Publication Year  1993

PubMed ID  8250931,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.