SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02483

Signal sequence   MLLILLSVALLAFSSA

Length  16

Organism  Homo sapiens (Human)

UniProt ID  P02810,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02483.cif

Structure  SPKB02483.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1662.10384

Aliphatic index  207.5

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  560.51

Aromaticity  0.0625

Average rotatable bonds  3.375

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  21

X logP energy  -1.3186

Hydropathy 



Literature Information


Title  Different isoforms and post-translational modifications of human salivary acidic proline-rich proteins.

DOI  10.1002/pmic.200401156,

Publication Year  2005

PubMed ID  15693058,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.