SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02482

Signal sequence   MKFLVFAFILALMVSMIGA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P02808,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02482.cif

Structure  SPKB02482.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2102.72564

Aliphatic index  148.9473684

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  633.37

Aromaticity  0.157894737

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  25

X logP energy  1.467

Hydropathy 



Literature Information


Title  Molecular basis of salivary proline-rich protein and peptide synthesis: cell-free translations and processing of human and macaque statherin mRNAs and partial amino acid sequence of their signal peptides.

DOI  10.1177/00220345870660021301,

Publication Year  1987

PubMed ID  3476566,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.