SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02481

Signal sequence   MARVLGAPVALGLWSLCWSLAIA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P02790,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02481.cif

Structure  SPKB02481.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2398.95304

Aliphatic index  148.6956522

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  828.67

Aromaticity  0.086956522

Average rotatable bonds  3.130434783

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  29

X logP energy  -3.10023

Hydropathy 



Literature Information


Title  Complete amino acid sequence of human hemopexin, the heme-binding protein of serum.

DOI  10.1073/pnas.82.1.73,

Publication Year  1985

PubMed ID  3855550,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.