General Information
SPKB ID SPKB02479
Signal sequence MKLVFLVLLFLGALGLCLA
Length 19
Organism Homo sapiens (Human)
UniProt ID P02788,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02479.cif
Physicochemical Information
Molecular weight 2034.67574
Aliphatic index 205.2631579
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 613.14
Aromaticity 0.105263158
Average rotatable bonds 3.526315789
Number of hydrogen bond donors 22
Number of hydrogen bond acceptors 23
X logP energy 2.4054
Hydropathy
Literature Information
Title One of two human lactoferrin variants exhibits increased antibacterial and transcriptional activation activities and is associated with localized juvenile periodontitis.
DOI 10.1128/IAI.71.11.6141-6147.2003,
Publication Year 2003
PubMed ID 14573629,
Patent ID NA,