SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02478

Signal sequence   MRLAVGALLVCAVLGLCLA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P02787,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02478.cif

Structure  SPKB02478.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1886.44614

Aliphatic index  190

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  649.02

Aromaticity  0

Average rotatable bonds  3.210526316

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -2.41233

Hydropathy 



Literature Information


Title  The primary structure of human serum transferrin. The structures of seven cyanogen bromide fragments and the assembly of the complete structure.

DOI  NA,

Publication Year  1983

PubMed ID  6833213,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.