SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02475

Signal sequence   MNQTAILICCLIFLTLSGIQG

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P02778,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8K2X,

Predicted Structure ID  SPKB02475.cif

Structure  SPKB02475.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2252.77344

Aliphatic index  153.3333333

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  835.28

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -6.2385

Hydropathy 



Literature Information


Title  Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3).

DOI  10.1046/j.1523-1747.1999.00581.x,

Publication Year  1999

PubMed ID  10233762,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.