SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02474

Signal sequence   MSSAAGFCASRPGLLFLGLLLLPLVVAFASA

Length  31

Organism  Homo sapiens (Human)

UniProt ID  P02776,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02474.cif

Structure  SPKB02474.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3093.77904

Aliphatic index  138.7096774

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  1061.56

Aromaticity  0.096774194

Average rotatable bonds  3.064516129

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  39

X logP energy  -6.70743

Hydropathy 



Literature Information


Title  Amino acid sequence of human platelet factor 4.

DOI  10.1073/pnas.74.6.2256,

Publication Year  1977

PubMed ID  267922,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.