SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02472

Signal sequence   MKRVLVLLLAVAFGHA

Length  16

Organism  Homo sapiens (Human)

UniProt ID  P02774,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02472.cif

Structure  SPKB02472.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1738.21084

Aliphatic index  170.625

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  616.42

Aromaticity  0.0625

Average rotatable bonds  3.5625

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  21

X logP energy  -1.13233

Hydropathy 



Literature Information


Title  Molecular basis for the three major forms of human serum vitamin D binding protein (group-specific component).

DOI  10.1021/bi00575a036,

Publication Year  1979

PubMed ID  218624,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.