SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02470

Signal sequence   MKWVTFLLLLFISGSAFS

Length  18

Organism  Rattus norvegicus (Rat)

UniProt ID  P02770,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02470.cif

Structure  SPKB02470.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2060.52494

Aliphatic index  130

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  680.75

Aromaticity  0.222222222

Average rotatable bonds  3.611111111

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -1.1304

Hydropathy 



Literature Information


Title  Rat liver pre-proalbumin: complete amino acid sequence of the pre-piece. Analysis of the direct translation product of albumin messenger RNA.

DOI  NA,

Publication Year  1977

PubMed ID  893447,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.