SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02464

Signal sequence   MKLLLLLLCLGLTLVCGHA

Length  19

Organism  Rattus norvegicus (Rat)

UniProt ID  P02761,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  2A2G,

Predicted Structure ID  SPKB02464.cif

Structure  SPKB02464.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2024.65554

Aliphatic index  205.2631579

Isoelectric point  8.241247528

Charge (pH=7)   0.964648925

Topological polar surface area  662.05

Aromaticity  0

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -0.4334

Hydropathy 



Literature Information


Title  Amino acid sequence of the precursor of rat liver alpha 2 micro-globulin.

DOI  NA,

Publication Year  1981

PubMed ID  6163771,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.