SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02463

Signal sequence   MRSLGALLLLLSACLAVSA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P02760,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02463.cif

Structure  SPKB02463.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1902.38424

Aliphatic index  180

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  709.71

Aromaticity  0

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  26

X logP energy  -5.26253

Hydropathy 



Literature Information


Title  Complete amino acid sequence of human alpha 1-microglobulin.

DOI  10.1016/0006-291x(81)91209-2,

Publication Year  1981

PubMed ID  6164372,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.