SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02461

Signal sequence   MKWVWALLLLAALGSGRA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P02753,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02461.cif

Structure  SPKB02461.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1956.42264

Aliphatic index  146.6666667

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  697.75

Aromaticity  0.111111111

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  23

X logP energy  -1.54553

Hydropathy 



Literature Information


Title  The complete amino acid sequence of human serum retinol-binding protein.

DOI  10.3109/03009738709178685,

Publication Year  1987

PubMed ID  2444024,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.