SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02459

Signal sequence   MLRGPGPGLLLLAVQCLGTAVPSTGASKSKR

Length  31

Organism  Homo sapiens (Human)

UniProt ID  P02751,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02459.cif

Structure  SPKB02459.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3079.71294

Aliphatic index  103.8709677

Isoelectric point  11.65159386

Charge (pH=7)   3.935412893

Topological polar surface area  1230.03

Aromaticity  0

Average rotatable bonds  3.225806452

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  44

X logP energy  -14.26236

Hydropathy 



Literature Information


Title  Primary structure of human plasma fibronectin. The 29,000-dalton NH2-terminal domain.

DOI  NA,

Publication Year  1983

PubMed ID  6630202,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.