General Information
SPKB ID SPKB02458
Signal sequence MSSWSRQRPKSPGGIQPHVSRTLFLLLLLAASAWG
Length 35
Organism Homo sapiens (Human)
UniProt ID P02750,
Motif 1..35
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8H24,
Predicted Structure ID SPKB02458.cif
Physicochemical Information
Molecular weight 3849.51484
Aliphatic index 94.85714286
Isoelectric point 12.80742811
Charge (pH=7) 4.088588423
Topological polar surface area 1526.12
Aromaticity 0.085714286
Average rotatable bonds 3.457142857
Number of hydrogen bond donors 55
Number of hydrogen bond acceptors 51
X logP energy -14.47329
Hydropathy 
Literature Information
Title Periodicity of leucine and tandem repetition of a 24-amino acid segment in the primary structure of leucine-rich alpha 2-glycoprotein of human serum.
Publication Year 1985
PubMed ID 3856868,
Patent ID NA,
