SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02457

Signal sequence   MISPVLILFSSFLCHVAIA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P02749,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02457.cif

Structure  SPKB02457.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2061.57144

Aliphatic index  164.2105263

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  667.7

Aromaticity  0.105263158

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  26

X logP energy  -1.6297

Hydropathy 



Literature Information


Title  Purification of apolipoprotein H (beta 2-glycoprotein I)-like protein from human follicular fluid.

DOI  10.1016/s1096-4959(00)00359-6,

Publication Year  2001

PubMed ID  11250549,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.