SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02450

Signal sequence   MYGKIIFVLLLSEIVSISA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P02724,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02450.cif

Structure  SPKB02450.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2096.59634

Aliphatic index  179.4736842

Isoelectric point  6.402001171

Charge (pH=7)   -0.001386026

Topological polar surface area  731.36

Aromaticity  0.105263158

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -1.6745

Hydropathy 



Literature Information


Title  Amino-acid sequence and oligosaccharide attachment sites of human erythrocyte glycophorin.

DOI  10.1073/pnas.72.8.2964,

Publication Year  1975

PubMed ID  1059087,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.