Peptide-Information

General Information

SPKB ID SPKB02448

Signal sequence MEPWPLLLLFSLCSAGLVLG

Length 20

Organism Homo sapiens (Human)

UniProt ID P02708,

Motif 1..20

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID 9DMG,

Predicted Structure ID SPKB02448.cif

Structure SPKB02448.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2159.67274

Aliphatic index 156

Isoelectric point 3.849962145

Charge (pH=7) -1.062215294

Topological polar surface area 692.19

Aromaticity 0.1

Average rotatable bonds 3.25

Number of hydrogen bond donors 24

Number of hydrogen bond acceptors 26

X logP energy -0.6177

Hydropathy

Literature Information

Title Amphipathic segment of the nicotinic receptor alpha subunit contains epitopes recognized by T lymphocytes in myasthenia gravis.

Publication Year 1988

PubMed ID 2449458,

Patent ID NA,