SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02444

Signal sequence   MSWSLHPRNLILYFYALLFLSSTCVA

Length  26

Organism  Homo sapiens (Human)

UniProt ID  P02679,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02444.cif

Structure  SPKB02444.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3046.63804

Aliphatic index  123.8461538

Isoelectric point  8.51416646

Charge (pH=7)   1.025214535

Topological polar surface area  1073.1

Aromaticity  0.192307692

Average rotatable bonds  3.538461538

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  39

X logP energy  -4.71363

Hydropathy 



Literature Information


Title  Evidence for the selective association of a subpopulation of GPIIb-IIIa with the actin cytoskeletons of thrombin-activated platelets.

DOI  10.1083/jcb.121.6.1329,

Publication Year  1993

PubMed ID  8509453,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.