SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02443

Signal sequence   MKRMVSWSFHKLKTMKHLLLLLLCVFLVKS

Length  30

Organism  Homo sapiens (Human)

UniProt ID  P02675,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02443.cif

Structure  SPKB02443.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3631.65114

Aliphatic index  133

Isoelectric point  11.36732006

Charge (pH=7)   6.116349285

Topological polar surface area  1253.29

Aromaticity  0.1

Average rotatable bonds  4.2

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  47

X logP energy  -2.60963

Hydropathy 



Literature Information


Title  Amino acid sequence of the beta chain of human fibrinogen.

DOI  10.1021/bi00568a011,

Publication Year  1979

PubMed ID  420779,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.