SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02442

Signal sequence   QVCIA

Length  5

Organism  Petromyzon marinus (Sea lamprey)

UniProt ID  P02674,

Motif  <1..5



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02442.cif

Structure  SPKB02442.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  532.65554

Aliphatic index  156

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  222.81

Aromaticity  0

Average rotatable bonds  3.2

Number of hydrogen bond donors  8

Number of hydrogen bond acceptors  8

X logP energy  -1.7452

Hydropathy 



Literature Information


Title  Amino acid sequences of lamprey fibrinopeptides A and B and characterizations of the junctions split by lamprey and mammalian thrombins.

DOI  10.1016/0005-2795(76)90138-0,

Publication Year  1976

PubMed ID  999898,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.