SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02433

Signal sequence   MQPRVLLVVALLALLASARA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P02656,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02433.cif

Structure  SPKB02433.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2105.65664

Aliphatic index  185.5

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  794.55

Aromaticity  0

Average rotatable bonds  3.4

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  26

X logP energy  -4.00276

Hydropathy 



Literature Information


Title  Amino acid sequence of human plasma apolipoprotein C-III from normolipidemic subjects.

DOI  10.1016/0014-5793(86)80300-3,

Publication Year  1986

PubMed ID  3949020,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.