SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02432

Signal sequence   MGTRLLPALFLVLLVLGFEVQG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P02655,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02432.cif

Structure  SPKB02432.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2386.96464

Aliphatic index  168.1818182

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  828.15

Aromaticity  0.090909091

Average rotatable bonds  3.5

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -1.69703

Hydropathy 



Literature Information


Title  Primary structure of very low density apolipoprotein C-II of human plasma.

DOI  10.1073/pnas.74.5.1942,

Publication Year  1977

PubMed ID  194244,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.