SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02428

Signal sequence   MKAALLTLAVLFLTGSQA

Length  18

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P02648,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02428.cif

Structure  SPKB02428.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1848.27434

Aliphatic index  146.6666667

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  687.82

Aromaticity  0.055555556

Average rotatable bonds  3.388888889

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -4.6184

Hydropathy 



Literature Information


Title  Mass spectral analysis of the apolipoproteins on dog (Canis lupus familiaris) high density lipoproteins. Detection of apolipoprotein A-II.

DOI  10.1016/j.cbd.2008.08.002,

Publication Year  2008

PubMed ID  20483223,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.