SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02426

Signal sequence   MLSFVDTRTLLLLAVTSCLATC

Length  22

Organism  Rattus norvegicus (Rat)

UniProt ID  P02466,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02426.cif

Structure  SPKB02426.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2371.89414

Aliphatic index  141.8181818

Isoelectric point  6.064584924

Charge (pH=7)   -0.12552196

Topological polar surface area  895

Aromaticity  0.045454545

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -7.69133

Hydropathy 



Literature Information


Title  Peptidomics for Studying Limited Proteolysis.

DOI  10.1021/acs.jproteome.5b00820,

Publication Year  2015

PubMed ID  26479776,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.