General Information
SPKB ID SPKB02424
Signal sequence MSWKKALRIPGGLRAATVTLMLAMLSTPVAEG
Length 32
Organism Homo sapiens (Human)
UniProt ID P01920,
Motif 1..32
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8VSP,
Predicted Structure ID SPKB02424.cif
Physicochemical Information
Molecular weight 3371.12134
Aliphatic index 106.875
Isoelectric point 11.65088967
Charge (pH=7) 2.999162732
Topological polar surface area 1277.92
Aromaticity 0.03125
Average rotatable bonds 3.4375
Number of hydrogen bond donors 46
Number of hydrogen bond acceptors 46
X logP energy -10.21856
Hydropathy 
Literature Information
Title Primary structure of human class II histocompatibility antigens 3rd communication. Amino acid sequence comparison between DR and DC subclass antigens derived from a lymphoblastoid B cell line homozygous at the HLA loci (HLA-A3,3; B7,7; Dw2,2; DR2,2: MT1,1; Dc1,1: MB1,1).
DOI 10.1515/bchm2.1983.364.1.749,
Publication Year 1983
PubMed ID 6576979,
Patent ID NA,
