General Information
SPKB ID SPKB02422
Signal sequence MILNKALMLGALALTTVMSPCGG
Length 23
Organism Homo sapiens (Human)
UniProt ID P01909,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6PX6,
Predicted Structure ID SPKB02422.cif
Physicochemical Information
Molecular weight 2305.89594
Aliphatic index 127.3913043
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 824.53
Aromaticity 0
Average rotatable bonds 3.304347826
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 33
X logP energy -6.596
Hydropathy 
Literature Information
Title Primary structure of human class II histocompatibility antigens 3rd communication. Amino acid sequence comparison between DR and DC subclass antigens derived from a lymphoblastoid B cell line homozygous at the HLA loci (HLA-A3,3; B7,7; Dw2,2; DR2,2: MT1,1; Dc1,1: MB1,1).
DOI 10.1515/bchm2.1983.364.1.749,
Publication Year 1983
PubMed ID 6576979,
Patent ID NA,
