General Information
SPKB ID SPKB02421
Signal sequence MAISGVPVLGFFIIAVLMSAQESWA
Length 25
Organism Homo sapiens (Human)
UniProt ID P01903,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8VRW,
Predicted Structure ID SPKB02421.cif
Physicochemical Information
Molecular weight 2638.17814
Aliphatic index 128.8
Isoelectric point 3.849983241
Charge (pH=7) -1.000240578
Topological polar surface area 909.8
Aromaticity 0.12
Average rotatable bonds 3.28
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 33
X logP energy -4.0966
Hydropathy 
Literature Information
Title N-terminal amino acid sequences of the alpha and beta chains of HLA-DR1 and HLA-DR2 antigens.
DOI 10.1021/bi00270a027,
Publication Year 1983
PubMed ID 6600932,
Patent ID NA,
